CD1b anticorps (N-Term)
Aperçu rapide pour CD1b anticorps (N-Term) (ABIN2774371)
Antigène
Voir toutes CD1b (CD1B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- N-Term
-
Séquence
- TAIFLKPWSK GNFSDKEVAE LEEIFRVYIF GFAREVQDFA GDFQMKYPFE
-
Homologie
- Cow: 86%, Dog: 79%, Guinea Pig: 83%, Horse: 86%, Human: 100%, Sheep: 86%
-
Attributs du produit
- This is a rabbit polyclonal antibody against CD1B. It was validated on Western Blot.
-
Purification
- Affinity Purified
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 333 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- CD1b (CD1B)
-
Autre désignation
- CD1B
-
Sujet
-
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
Alias Symbols: CD1, CD1A, MGC125990, MGC125991, R1
Protein Interaction Partner: UBC, PSAP, B2M,
Protein Size: 333 -
Poids moléculaire
- 37 kDa
-
ID gène
- 910
-
NCBI Accession
- NM_001764, NP_001755
-
UniProt
- P29016
Antigène
-